Immunocytochemical and ultrastructural differentiation between Met- enkephalin-, Leu-enkephalin-, and Met/Leu-enkephalin-immunoreactive neurons of feline gut
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منابع مشابه
Immunocytochemical and ultrastructural differentiation between Met-enkephalin-, Leu-enkephalin-, and Met/Leu-enkephalin-immunoreactive neurons of feline gut.
Selective immunocytochemical procedures, applied at the light and electron microscopical level, have resulted in the identification of three types of enkephalin-immunoreactive nerves in the feline gastrointestinal tract, including neurons containing either Met- or Leu-enkephalin immunoreactivity or those simultaneously storing both Met- and Leu-enkephalin immunoreactants. The three different ty...
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Adrenal chromaffin granules contain at least 10 peptides, ranging in size from 3 to 5 kilodaltons, that yield, upon digestion with trypsin, peptides that show specific binding to opiate receptors. All are distinctly different from beta-endorphin. Two of these peptides have been purified to homogeneity and subjected to chemical analysis. One is apparently a [Met]enkephalin precursor containing t...
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Leu-enkephalin is an opioid peptide that has been found to modulate nociception in the spinal cord. Both pre- and postsynaptic interactions by enkephalins have been proposed. By the peroxidase . anti-peroxidase immunocytochemical method, we studied the distribution and ultrastructure of neuronal elements in the monkey dorsal horn to elucidate possible morphological substrates for postulated opi...
متن کاملImmunocytochemical studies with antisera against leu-enkephalin and an enkephalin-precursor fragment (BAM-22P) in the rat brain.
Rats given high doses of colchicine (300-400 ug, i.c.v.) were used to investigate the comparative distribution of Leu-enkephalin and bovine adrenal medullary enkephalinprecursor fragment (BAM-22P) in the brain. Leu-enkephalin immunoreactive neurons have a widespread distribution throughout the neuraxis. In most areas adjacent section analysis showed BAM-22P and Leu-enkephalin immunoreactive per...
متن کاملImmunohistochemical studies on the gastrointestinal tract using antisera to Met-enkephalin and Met-enkephalin Arg6Phe7.
Antisera specific for the C-terminus of Met-enkephalin and two of its variants isolated from adrenal medulla and brain, namely Met-enk Arg6 and Met-enk Arg6Phe7, have been used in immunohistochemical studies of the gastrointestinal tract in rat, mouse and guinea pig. Met-enk and Met-enk Arg6Phe7-like immunoreactivities were found with similar distribution in nerve cell bodies of the myenteric p...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1982
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.02-07-00861.1982